Henri Guillaume Schlesinger (also Heinrich Wilhelm Schlesinger, born August 6, 1814 in Frankfurt am Main, died February 21, 1893 in Neuilly-sur-Seine) was a German portrait and genre painter. Besides the oil painting, he used it to paint watercolor and miniature painting on ivory.

Schlesinger studied painting at the Academy of Fine Arts in Vienna and was first active in Vienna. He then moved to Paris, and continues his artistic education. In the period 1840-1889, he exhibited his work at the Paris Salon. In 1837, Henri-Guillaume Schlesinger made several official portraits, including a large equestrian portrait of Sultan Mahmoud II. In the years 1870-1871, he lived in London.

Schlesinger received the Legion of Honor in 1866 and received French citizenship in 1870.